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| Campo DC | Valor | Idioma |
|---|---|---|
| dc.contributor.advisor | Filho, Edson Luiz Cetira | - |
| dc.contributor.author | Anjos, Mayara Alves dos | - |
| dc.date.accessioned | 2025-06-26T13:45:57Z | - |
| dc.date.available | 2025-06-26T13:45:57Z | - |
| dc.date.issued | 2025-06-26 | - |
| dc.identifier.uri | https://repositorio.unichristus.edu.br/jspui/handle/123456789/1924 | - |
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DOI: https://doi.org/10.1155/2019/2864216. Disponível em: https://onlinelibrary.wiley.com/doi/10.1155/2019/2864216. Acesso em: 24 jan. 2024. | pt_BR |
| dc.description.abstract | Objetivou-se responder se, em (P) indivíduos submetidos à cirurgia ortognática, (I) a analgesia preemptiva antes do procedimento cirúrgico em comparação com (C) terapia farmacológica ou ausência de terapia, pode melhorar o (O) quadro clínico de dor e reduzir o consumo de medicamentos e efeitos adversos em (S) ensaios clínicos randomizados. Uma busca eletrônica preliminar foi realizada seguindo um alfabeto latino (romano) em bases de bancos de dados indexadas e literatura cinzenta, sem restrição de idioma, sexo ou ano de publicação. O risco de viés foi realizado pela ferramenta RoB 2.0, e a meta- análise utilizou diferenças médias (MD) para consumo de medicação de resgate e efeitos adversos e diferenças médias padronizadas (SMD) para escores de dor (p < 0,05, Revman®). Foram incluídos 171 pacientes no grupo controle e 212 pacientes submetidos à analgesia preemptiva. Quanto à dor, houve redução significativa de -1,32 (-1,51, -1,13) escores de dor (p<0,001) com alto impacto clínico d de Cohen de -0,91 (-1,05, -0,77). Houve heterogeneidade moderada significativa (p<0,001, I2 = 68%) e diferença significativa entre os períodos de avaliação (p<0,001, I2 = 67,3%). Apesar do baixo risco de viés, a heterogeneidade foi de média a alta entre os estudos (I2: 27 a 89%) e o pequeno tamanho amostral tornaram a certeza da evidência GRADE baixa a moderada. Esta RS demonstrou que o uso de analgésicos e anti-inflamatórios de uso preemptivo controlam eficazmente a dor e reduzem o consumo de medicação de resgate após cirurgia ortognática. | pt_BR |
| dc.subject | cirurgia ortognática | pt_BR |
| dc.subject | dor | pt_BR |
| dc.subject | analgesia preemptiva | pt_BR |
| dc.subject | farmacologia | pt_BR |
| dc.title | A EFICÁCIA DA ANALGESIA PREEMPTIVA NA REDUÇÃO DA DOR EM CIRURGIA ORTOGNÁTICA: UMA REVISÃO SISTEMÁTICA COM META- ANÁLISE DE ENSAIOS CLÍNICOS RANDOMIZADOS. | pt_BR |
| dc.type | TCC | pt_BR |
| dc.title.ingles | THE EFFICACY OF PREEMPTIVE ANALGESIA IN REDUCING PAIN IN ORTHOGNATHIC SURGERY: A SYSTEMATIC REVIEW WITH META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS | pt_BR |
| dc.description.resumo_abstract | This Systematic Review (SR) aimed to answer whether, in (P) individuals undergoing orthognathic surgery, (I) preemptive analgesia before the surgical procedure compared to (C) pharmacologic therapy or absence of therapy for improvement of the (O) clinical picture of pain, drug consumption and adverse effects in (S) randomized clinical trials. A preliminary electronic search was conducted for references with language following a Latin (Roman) alphabet in sex databases index, and gray literature without restriction on language or publication period. Risk of bias was performed by RoB 2.0 tool, and meta- analysis used mean differences (MD) for consumption of rescue medication and adverse effects and standardized mean differences (SMD) for pain scores (p < 0.05, Revman®). A total of 171 control patients and 212 patients undergoing preemptive analgesia were included. As for pain, there was a significant reduction of -1.32 (-1.51, -1.13) pain scores (p<0.001) with a high clinical impact Cohen's d of -0.91 (-1.05, -0.77). There was significant moderate heterogeneity (p<0.001, I2 = 68%) and a significant difference between the evaluation periods (p<0.001, I2 = 67.3%). Despite the low risk of bias, medium to high heterogeneity among studies (I2: 27 to 89%) and small sample sizes made the certainty of GRADE evidence low to moderate. This SR demonstrated that the use of analgesic and anti-inflammatory drugs used preemptively effectively controls pain and reduces the consumption of rescue medication after orthognathic surgery. | pt_BR |
| Aparece nas coleções: | Odontologia - Campus PARQUE ECOLÓGICO | |
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