A EFICÁCIA DA ANALGESIA PREEMPTIVA NA REDUÇÃO DA DOR EM CIRURGIA ORTOGNÁTICA: UMA REVISÃO SISTEMÁTICA COM META- ANÁLISE DE ENSAIOS CLÍNICOS RANDOMIZADOS.

Anjos, Mayara Alves dos

Use este identificador para citar ou linkar para este item: https://repositorio.unichristus.edu.br/jspui/handle/123456789/1924

Título:	A EFICÁCIA DA ANALGESIA PREEMPTIVA NA REDUÇÃO DA DOR EM CIRURGIA ORTOGNÁTICA: UMA REVISÃO SISTEMÁTICA COM META- ANÁLISE DE ENSAIOS CLÍNICOS RANDOMIZADOS.
Autor(es):	Anjos, Mayara Alves dos
Orientador:	Filho, Edson Luiz Cetira
Data do documento:	2025-06-26
Resumo:	Objetivou-se responder se, em (P) indivíduos submetidos à cirurgia ortognática, (I) a analgesia preemptiva antes do procedimento cirúrgico em comparação com (C) terapia farmacológica ou ausência de terapia, pode melhorar o (O) quadro clínico de dor e reduzir o consumo de medicamentos e efeitos adversos em (S) ensaios clínicos randomizados. Uma busca eletrônica preliminar foi realizada seguindo um alfabeto latino (romano) em bases de bancos de dados indexadas e literatura cinzenta, sem restrição de idioma, sexo ou ano de publicação. O risco de viés foi realizado pela ferramenta RoB 2.0, e a meta- análise utilizou diferenças médias (MD) para consumo de medicação de resgate e efeitos adversos e diferenças médias padronizadas (SMD) para escores de dor (p < 0,05, Revman®). Foram incluídos 171 pacientes no grupo controle e 212 pacientes submetidos à analgesia preemptiva. Quanto à dor, houve redução significativa de -1,32 (-1,51, -1,13) escores de dor (p<0,001) com alto impacto clínico d de Cohen de -0,91 (-1,05, -0,77). Houve heterogeneidade moderada significativa (p<0,001, I2 = 68%) e diferença significativa entre os períodos de avaliação (p<0,001, I2 = 67,3%). Apesar do baixo risco de viés, a heterogeneidade foi de média a alta entre os estudos (I2: 27 a 89%) e o pequeno tamanho amostral tornaram a certeza da evidência GRADE baixa a moderada. Esta RS demonstrou que o uso de analgésicos e anti-inflamatórios de uso preemptivo controlam eficazmente a dor e reduzem o consumo de medicação de resgate após cirurgia ortognática.
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Palavras-chave:	cirurgia ortognática dor analgesia preemptiva farmacologia
URI:	https://repositorio.unichristus.edu.br/jspui/handle/123456789/1924
Aparece nas coleções:	Odontologia - Campus PARQUE ECOLÓGICO

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